June 17, 2025
As skin scientists and cosmetic chemists, we’ve long known that not all rose oils are created equal. The difference lies not only in the species of rose used, but also in the harvesting method, extraction technique, and geographical origin of the flower. Each factor contributes profoundly to the oil’s quality, purity, and therapeutic benefit to the skin.
The Three Main Types of Rose Oil
There are three primary types of rose-derived oils commonly used in skincare:
1. Rose Otto (Steam-Distilled Essential Oil)
Often referred to as the “liquid gold” of the skincare world, Rose Otto is produced through gentle steam distillation. This meticulous process preserves the volatile, heat-sensitive compounds that give the oil its characteristic aroma and potent biological activity. Rose Otto contains a symphony of actives—including citronellol, geraniol, and nerol—that provide soothing, anti-inflammatory, and microbiome-supportive benefits.
2. Rose Absolute (Solvent-Extracted)
While Rose Absolute boasts an intense aroma prized in perfumery, its solvent-based extraction process may leave behind trace residues. Though rich in fragrance compounds, absolutes often lack the full therapeutic profile necessary for clinical-grade skincare and may pose sensitivity risks for reactive skin.
3. Rosehip Oil (Cold-Pressed from Rosehip Seeds)
Though not derived from rose petals, rosehip oil is often confused with rose essential oils. This carrier oil is abundant in vitamins A and C and offers regenerative benefits, but lacks the aromatic and anti-inflammatory properties of true rose essential oil.
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From Petal to Elixir: How Rose Otto Is Made
At Luksha, we source only the highest grade Organic Rose Otto essential oil, harvested at peak bloom on a certified organic farm in the Valley of Roses, Bulgaria—the world’s most renowned region for Rosa damascena cultivation. Each rose must be hand-picked during the early morning hours, when the flower’s volatile compounds are at their peak concentration.
By midday, these fresh petals are gently steam-distilled—no solvents, no shortcuts. This immediate distillation captures not just the scent, but the complete therapeutic profile of the flower, including its calming, antioxidant, and skin-balancing properties. The result is an oil that not only smells exquisite, but genuinely supports skin health on a cellular level.
This method stands in sharp contrast to solvent extraction, which may yield more oil but compromises its purity and biological integrity.
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A Precious Yield
To produce just 1 kilogram of Organic Rose Otto, it takes approximately 3,000 to 5,000 kilograms of freshly harvested rose petals—equivalent to over 1 million blossoms. This staggering yield reflects the sheer concentration and potency of the oil, as well as its exceptional cost and rarity.
Even at a concentration of just 0.01% to 0.05%, Rose Otto remains therapeutically active, delivering clinically relevant benefits without overwhelming the skin or triggering sensitivity.
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Rose Season at Luksha
June is rose season in full bloom, and at Luksha, it’s the time we begin crafting one of our most elegant and beloved formulations:
Nourishing Cream with Raspberry Seed Oil and Organic Rose Otto.
This luxurious formula blends skin-nourishing botanical lipids with the pure essence of Bulgarian Rose Otto to calm, hydrate, and restore radiance—especially for mature or sensitive skin.
Other Luksha products enriched with Organic Rose Otto or Organic Rose Water include:
Moisturising Cream-Mask – A deeply hydrating treatment that replenishes the skin barrier while calming irritation.
Toner with Organic Rose Water, Organic Cranberry Extract, and Organic Aloe Leaf Juice
– A gentle mist that tones, softens, and refreshes with the natural humectant power of rose.
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Why We Choose Rose Otto
As cosmetic chemists and skin specialists, we formulate not just for aroma, but for efficacy. Rose Otto’s chemical composition supports barrier function, reduces inflammation, and helps balance the skin’s microbiome—making it ideal for sensitive, dry, and mature skin types. Its unique synergy of molecules is impossible to replicate with lower-grade alternatives.
At Luksha, we choose Rose Otto because it is the best.
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References:
1. Avetisyan, A., et al. (2017). Chemical composition and antimicrobial activity of essential oil of Rosa damascena. Journal of Essential Oil Research.
2. Lawrence, B.M. (2007). A study of rose oil composition. Perfumer & Flavorist.
3. Sofia, D.S., et al. (2019). Therapeutic properties of Rosa damascena Mill. on skin: A review. Phytotherapy Research.
4. International Federation of Essential Oils and Aroma Trades (IFEAT) – Rose Oil Market Overview.
5. Luksha Cosmetics Internal Formulation Records, 2025.
June 01, 2025
In the evolving world of skincare, savvy consumers are no longer satisfied with just knowing what’s in their products — they want to understand how those ingredients work. One of the most exciting advancements in formulation science today is the use of lamellar structure technology. Found in next-generation products like Luksha’s Eco-Balance Probiotic Radiance Cream and Eco-Balance Night Cream, lamellar systems are transforming the way active ingredients interact with your skin.
Let’s explore what lamellar structure actually is, and why it’s considered one of the most sophisticated, skin-intelligent delivery systems in modern cosmetic science.
What Is a Lamellar Structure in Skincare?
A lamellar structure refers to a microscopic, layered arrangement of lipids and water that closely mimics the skin’s natural barrier. Specifically, it imitates the stratum corneum, the outermost layer of the skin, which is composed of flattened skin cells surrounded by lipid bilayers — arranged in thin, sheet-like layers known as lamellae.
This design is not only biologically familiar to your skin — it’s functionally smarter than conventional emulsions.
Why This Matters: Mimicking Nature for Maximum Benefit
Your skin recognizes the lamellar structure as “self,” which significantly improves compatibility, absorption, and effectiveness. Unlike conventional creams where ingredients may sit on the surface or evaporate, lamellar formulations integrate seamlessly into the skin barrier.
Luksha’s formulations — like the Moisturising Cream-Mask — leverage this structure to support skin’s natural repair and hydration cycles without overwhelming it.
5 Reasons Lamellar Skincare Is Changing the Game:
1. Enhanced Skin Compatibility
Lamellar creams are especially suited to sensitive, reactive, or barrier-compromised skin. Because their structure mirrors the skin’s own lipid matrix, they reduce the risk of irritation or incompatibility.
Example: Luksha’s Eco-Balance Probiotic Radiance Cream uses lamellar technology to deliver prebiotics and other actives with maximum tolerance — even for delicate skin types.
2. Smarter Delivery of Actives
In lamellar emulsions, actives such as niacinamide, ceramides, peptides, or plant extracts are embedded between the layers, enabling sustained release and deeper penetration.
Example: Luksha’s Eco-Balance Night Cream provides nighttime support with soothing and reparative actives delivered gradually throughout the skin’s overnight regeneration phase.
3. Deep, Long-Lasting Hydration
The layered water-and-lipid design functions as a moisture reservoir, slowly releasing hydration over time. This ensures the skin remains plump and hydrated without greasiness.
Example: Luksha’s Moisturising Cream-Mask offers a luxurious, lamellar-based boost of moisture that continues to hydrate long after application — perfect as a weekly treatment or overnight mask.
4. Reinforces the Skin Barrier
By delivering essential skin-identical lipids (like ceramides and fatty acids) in a familiar structure, lamellar formulations help restore and fortify the skin barrier.
All three Luksha creams contribute to barrier repair through a structure that works with the skin, not against it — an ideal choice for those facing urban pollution, dehydration, or stress-induced sensitivity.
5. Lightweight Texture, High-Performance Results
Despite being rich in function, lamellar products typically feel silky, breathable, and non-occlusive. They provide a “second skin” effect that doesn’t clog pores or feel heavy.
Luksha’s lamellar creams are formulated to absorb quickly, making them ideal for layering under sunscreen or makeup while still providing deep nourishment.
Lamellar Isn’t a Buzzword — It’s a Breakthrough
Developing a stable lamellar emulsion requires a precise balance of skin-identical lipids, emulsifiers, and pH conditions. These systems are more technically demanding than traditional emulsions — but the result is a formulation that aligns with how your skin naturally protects and repairs itself.
Luksha: A Leader in Lamellar Skincare
At Luksha, we believe that smart skincare starts with structure. Our lamellar formulations — including the Eco-Balance Probiotic Radiance Cream, Eco-Balance Night Cream, and Moisturising Cream-Mask — are designed with ingredient integrity, skin biology, and long-term results in mind.
Whether you’re rebuilding your barrier or simply seeking a more intelligent way to hydrate and glow, lamellar technology represents the next evolution in skincare — and we’re proud to be part of that movement.
References
1. Elias, P.M. (2005). Stratum corneum defensive functions: an integrated view. Journal of Investigative Dermatology, 125(2), 183–200.
2. Voegeli, R., Rawlings, A.V. (2020). Delivering actives into the skin: the role of lamellar emulsion technology. Cosmetics & Toiletries, 135(5), 42–51.
3. Morganti, P., Ruocco, E., & Wolf, R. (2011). Percutaneous absorption and delivery systems. Clinics in Dermatology, 29(2), 185–189.
4. Rawlings, A.V., & Harding, C.R. (2004). Moisturization and skin barrier function. Dermatologic Therapy, 17(s1), 43–48.
5. Blume-Peytavi, U., Vogt, A. (2011). Skin physiology: relevance for dermatological practice. American Journal of Clinical Dermatology, 12(4), 247–257.
May 24, 2025
Vitamin C is a cornerstone of modern skincare for good reason: it’s clinically proven to brighten skin, support collagen production, and defend against environmental oxidative stress. But among the many forms of vitamin C used in cosmetics, L-ascorbic acid stands alone as the most biologically active—and the most challenging to formulate.
What Makes L-Ascorbic Acid Superior?
As the chemically identical form of vitamin C found in the human body, L-ascorbic acid requires no conversion by the skin. Its low molecular weight (176.12 Da) and optimal activity at a pH of ~3.5 allow it to penetrate effectively into the epidermis, where it:
• Acts as a cofactor in collagen synthesis
• Inhibits tyrosinase, helping to fade hyperpigmentation
• Neutralizes free radicals caused by UV light and pollution
Unlike stabilized derivatives such as magnesium ascorbyl phosphate or ascorbyl glucoside—which must be enzymatically converted into L-ascorbic acid within the skin, often inefficiently—L-ascorbic acid works directly and immediately.
The Challenge of Stability
Despite its efficacy, L-ascorbic acid is notoriously unstable. It rapidly degrades when exposed to light, air, or water—losing potency and potentially generating irritating byproducts. This instability is why many mass-market brands avoid it or rely on derivatives that trade performance for shelf life.
Luksha’s Advanced Solution
At Luksha, we’ve taken a different path. Our Intensive Brightening Serum delivers 15% pure L-ascorbic acid in a formulation designed for maximum freshness and potency. To preserve the integrity of this powerful antioxidant, we produce the serum seasonally in small batches, ensuring each unit reaches the customer with optimal activity.
Do you know any other brand that approaches skincare with such precision and dedication to quality?
It’s labor-intensive, yes—but our passion for efficacy and integrity makes it worth it.
This approach allows Luksha to offer what many cannot: the true efficacy of clinical-grade vitamin C, uncompromised by mass-production shortcuts.
The Result?
A high-performance, scientifically sound vitamin C serum - Intensive Brightening Serum from Luksha laboratory - that delivers:
• Visible brightness
• Enhanced skin resilience
• Long-term dermal support
Science. Freshness. Efficacy. That’s the Luksha difference.
References:
1. Pinnell SR, et al. (2001).
Topical L-ascorbic acid: percutaneous absorption studies.
Dermatologic Surgery, 27(2), 137-142.
2. Telang PS. (2013).
Vitamin C in dermatology.
Indian Dermatology Online Journal, 4(2), 143–146.
3. Traikovich SS. (1999).
Use of topical ascorbic acid and its effects on photodamaged skin topography.
Archives of Otolaryngology–Head & Neck Surgery, 125(10), 1091–1098.
4. Darr D, Combs S, Dunston S, Manning T, Pinnell S. (1996).
Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage.
British Journal of Dermatology, 135(4), 688–694.
5. Humbert PG, et al. (2003).
Topical ascorbic acid on photoaged skin.
Clinical, Cosmetic and Investigational Dermatology.
6. Farris PK. (2005).
Topical vitamin C: a useful agent for treating photoaging and other dermatologic conditions.
Dermatologic Surgery, 31(s1), 814–818.
7. Pullar JM, Carr AC, Vissers MC. (2017).
The roles of vitamin C in skin health.
Nutrients, 9(8), 866.
May 01, 2025
What if your skincare routine could do more than hydrate and soften—what if it could activate your skin’s own biological intelligence? Luksha’s Cellular Cream is built on this philosophy. It combines advanced biomimetic actives and clinically studied botanical technologies to target aging at its source—from deep dermal restructuring to epidermal renewal.
This multi-layered approach leverages three exceptional ingredients: Gladback™, a dermal fortifier derived from medicinal mycology; Decorinyl®, a peptide that mimics skin’s structural regulators; and PhytoCellTec™ Malus Domestica, a patented apple stem cell technology that helps preserve skin’s regenerative power. Each ingredient plays a precise role, working in synergy to help your skin look and function at its best.
1. PhytoCellTec™ Malus Domestica (Apple Stem Cell Extract, Switzerland
Inspired by the longevity of the rare Swiss apple Uttwiler Spätlauber, this stem cell technology supports the skin’s own epidermal stem cells—the source of continuous skin renewal.
Mechanism of Action:
Shields human epidermal stem cells from UV-induced oxidative stress and apoptosis, preserving their function over time
Enhances mitochondrial activity and ATP synthesis, energizing basal keratinocytes for improved epidermal turnover.
Clinically proven to reduce wrinkle depth by 15% within 4 weeks, contributing to smoother, more youthful-looking skin.
Liposomal encapsulation ensures penetration to the basal layers where stem cells reside.
2. Gladback™ (Poria cocos-based active for mature skin), Spain
Gladback™ is derived from Poria cocos, a revered medicinal mushroom used in Traditional Chinese Medicine. It offers targeted support for mature, stressed, or hormonally imbalanced skin.
Mechanism of Action:
Increases dermal thickness and microvascular density, improving skin firmness and tone. Clinical ultrasound imaging confirmed enhanced dermal echogenicity in postmenopausal subjects after 28 days of use.
Stimulates collagen I synthesis while suppressing MMP-1 activity, protecting the extracellular matrix from breakdown.
Brightens and revitalizes the skin by improving oxygen and nutrient delivery through enhanced microcirculation.
Delivers antioxidant and anti-inflammatory benefits via triterpene compounds, mitigating oxidative stress and inflammaging.
3. Decorinyl® – Tripeptide-10 Citrulline Complex, France
Decorinyl® is a biomimetic peptide inspired by decorin, a natural regulator of collagen fiber organization. As skin ages, collagen becomes irregular and fragmented—this peptide helps restore structure.
54% increase in skin suppleness after 28 days.
Mechanism of Action:
Modulates collagen fibril spacing and diameter, improving mechanical properties and elasticity.
Reduces wrinkle depth and surface roughness. In clinical trials, participants saw up to a 14% improvement in skin smoothness after 4 weeks of use.
Controls MMP activity to maintain balanced matrix turnover and prevent degradation of structural proteins.
Uses a phospholipid-based delivery system (lecithin) to optimize bioavailability, while caprylyl glycol maintains hydration and product stability.
Conclusion:
Cellular Cream is a meticulously engineered formulation developed to support the skin’s structural integrity and long-term vitality. Its fresh, small-batch production ensures maximum potency and stability, avoiding the compromises of mass manufacturing.
Designed with both precision and purpose, this cream works in harmony with the skin’s own biology—delivering visible results while respecting its natural rhythm.
References:
Li, J. et al. (2019). Anti-inflammatory effects of Poria cocos polysaccharides in macrophages. Journal of Ethnopharmacology, 241, 112549.
Lee, B. et al. (2018). Poria cocos-derived polysaccharides regulate tight junction proteins. Archives of Pharmacal Research, 41, 1236–1244.
Kim, S. et al. (2021). Hydrating effects of β-glucans and AQP3 stimulation. Cosmetics, 8(3), 76.
Zampar, A. et al. (2010). Role of decorin in collagen organization. Biochimica et Biophysica Acta, 1802(10), 1004–1010.
April 08, 2025
Skin ageing is a complex, multifactorial biological process—and one of the most visible signs of ageing in the human body. Fine lines, wrinkles, sagging, dullness, dryness, and uneven tone don’t appear overnight. They are the result of cumulative changes taking place within the skin’s structural, biochemical, and functional systems.
Understanding what drives these changes—both from within and from the environment—empowers us to make informed decisions about how to care for our skin through science-based topical treatments and internal wellness strategies.
What Causes Skin Ageing?
Collagen & Elastin Breakdown: The Structural Decline
Collagen accounts for approximately 75% of the skin’s dry weight and is responsible for its firmness and strength. Elastin gives skin its ability to stretch and rebound. With age, both collagen and elastin production naturally decline, and environmental stressors like UV exposure, pollution, and smoking accelerate their degradation.
A major internal contributor is glycation—a process where sugar molecules bind to collagen and elastin fibers, forming Advanced Glycation End-products (AGEs). These AGEs stiffen skin proteins, reducing elasticity and contributing to wrinkles and sagging.
Autophagy Decline: A Sluggish Cellular Cleanup
Autophagy is the skin’s internal recycling process. It removes damaged cellular components, allowing for healthier cell renewal. With age, this process slows, leading to a buildup of cellular debris and slower regeneration.
Interventions such as intermittent fasting and regular exercise may help reactivate autophagy and refresh the skin from within.
Oxidative Stress & Free Radicals: The Invisible Attackers
Free radicals—unstable molecules produced during normal metabolism—are amplified by sun exposure, pollution, poor nutrition, stress, and smoking. When they outnumber antioxidants in the skin, they create oxidative stress, which damages cellular structures including DNA, lipids, and proteins like collagen.
Antioxidants like vitamin C, vitamin E, glutathione, and coenzyme Q10 can help neutralize these radicals and protect the skin from premature ageing.
Inflammaging: Low-Grade Inflammation, Long-Term Damage
Inflammaging refers to chronic, low-grade inflammation that persists with age—even in the absence of infection or injury. This ongoing inflammatory state disrupts collagen synthesis, impairs the skin barrier, and contributes to dullness and sagging. It is influenced by UV radiation, hormonal imbalances, stress, poor sleep, and high-glycemic diets.
Chronic Dehydration: Starved Skin Cells
Many people suffer from subclinical dehydration. When the skin lacks water, it appears dry, dull, and more wrinkled. Dehydration slows cellular turnover and reduces enzymatic activity, limiting the skin’s natural renewal process.
While ingredients like hyaluronic acid can help attract moisture to the outer layers of the skin, systemic hydration—through adequate water intake—is essential for maintaining long-term skin health.
Compromised Skin Barrier: The Frontline Weakens
The skin barrier—primarily located in the stratum corneum—protects against environmental stressors and prevents moisture loss. Ageing weakens this barrier through lipid depletion and structural disorganization, resulting in increased transepidermal water loss (TEWL), dryness, and heightened sensitivity.
Supportive ingredients like ceramides, niacinamide, and omega fatty acids are essential to strengthen and repair the barrier.
Modern skin science offers a wide array of actives that can address various signs of ageing. Here are some of the most effective, along with product examples that showcase them:
Vitamin C
A potent antioxidant that promotes collagen synthesis, neutralizes free radicals, and brightens hyperpigmentation.
Try: Intensive Brightening Serum with 15% L-Ascorbic Acid, 2% Panthenol & 0.6% Ferulic Acid – improves tone, texture, and pigmentation.
Radiance Facial Concentrate with Cranberry and Vitamins C&E - for radiant and revitalized complexion.
Retinol (Vitamin A)
Stimulates collagen production, speeds cell turnover, and reduces uneven pigmentation.
Try: Intensive Pore & Oil Control Serum with Willow Bark Extract, Retinol, and Tea Tree Oil – helps regenerate skin and improve glow. In this formula, retinol is encapsulated within a liposomal form of vitamin A and carefully engineered for gradual, sustained release—delivering powerful skin-renewing benefits with minimal risk of irritation.
Bakuchiol
A plant-derived alternative to retinol that delivers similar results without the associated sensitivity.
Try: Luminous Balance Cream with 10% Azelaic Acid, 5% Niacinamide & Aloe Vera – combines bakuchiol with anti-inflammatory and barrier-supporting ingredients.
Peptides
Signal molecules that stimulate collagen, elastin, and keratin production, improving firmness and texture.
Try: Cellular Cream with Plant Stem Cells, Contouring Multi-Action Cream with Peptides, Vitamin C, and Coenzyme Q10, and Uplifting Eye Cream with Edelweiss Extract – all rich in bioactive peptides to visibly smooth and strengthen the skin.
Read the related article.
Ceramides
Key components of Stratum Corneum, essential skin lipids that maintain barrier integrity and retain moisture.
Try award winner: Eco-Balance Probiotic Radiance Cream with Pomegranate Seed Oil and Coenzyme Q10 – deeply restorative and soothing.
Niacinamide (Vitamin B3)
A multitasking vitamin that brightens, refines pores, strengthens the skin barrier, and regulates oil production.
Try: Intensive Hydrating Serum with Edelweiss, Hyaluronic Acid & Provitamin B5, Eco-Balance Blemish Defence Serum with Phages and Niacinamide, and Luminous Balance Cream with Azelaic Acid & Niacinamide
Hyaluronic Acid (HA)
A powerful humectant that hydrates and plumps the skin, helping reduce fine lines.
Try award winner: Intensive Hydrating Serum with Edelweiss, Hyaluronic Acid & Provitamin B5 – instantly replenishes moisture and soothes dryness.
A Holistic Approach: Supporting the Skin From Within
Topical skincare is essential, but for optimal and lasting results, internal wellness must not be overlooked.
Protein and Collagen Support
Your body needs amino acids from protein-rich foods like meat, fish, eggs, legumes, and seeds to produce collagen and elastin. Vitamin C is also required to support this synthesis.
Collagen supplements can be beneficial, particularly for vegetarians or individuals with low protein intake. However, in the context of a well-balanced diet, additional supplementation may offer limited benefit and, in some cases, could disrupt nutrient balance, promote inflammation, or interfere with the body’s natural autophagy processes.
Avoiding refined sugar and processed carbohydrates is key to reducing glycation and preserving skin integrity.
Anti-Inflammatory & Antioxidant-Rich Nutrition
Colorful fruits and vegetables provide phytonutrients like lycopene, lutein, and beta-carotene that protect against oxidative stress and UV-induced damage. Healthy fats from flax, chia, walnuts, avocado, and cold-pressed olive oil support the skin barrier and reduce inflammation.
A diverse, plant-forward diet also supports gut health—a major factor in systemic and skin-related inflammation.
Hydration
Proper hydration enhances cellular function, improves circulation, and supports nutrient delivery to the skin. Drink plenty of clean, filtered water and reduce consumption of dehydrating beverages like alcohol and excessive caffeine.
Even minor dehydration can exaggerate fine lines and slow skin healing.
The Bottom Line
Skin ageing is driven by a combination of genetic, environmental, and lifestyle factors. Topical treatments offer targeted, science-backed support—but sustainable beauty stems from within.
Combining advanced formulations with healthy habits creates the most effective approach to graceful, healthy ageing. Your skin is a reflection of your overall vitality. Nourish it inside and out—and it will reward you with lasting radiance.
References
Baumann, L. (2007). Cosmetic Dermatology: Principles and Practice. McGraw-Hill Education.
Varani, J., Dame, M.K., Rittie, L., et al. (2006). Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. American Journal of Pathology, 168(6), 1861–1868.
Ganceviciene, R., Liakou, A.I., Theodoridis, A., et al. (2012). Skin anti-aging strategies. Dermato-Endocrinology, 4(3), 308–319.
Bosset, S., Bonnet-Duquennoy, M., Barré, P., et al. (2003). Photoaging shows histological features of chronic skin inflammation without clinical and molecular abnormalities. British Journal of Dermatology, 149(4), 826–835.
Zouboulis, C.C., Makrantonaki, E. (2011). Clinical aspects and molecular diagnostics of skin aging. Clinical Dermatology, 29(1), 3–14.
Pullar, J.M., Carr, A.C., Vissers, M.C. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866.
Draelos, Z.D. (2015). Aging skin: The role of dietary antioxidants and their impact on cosmetic dermatology. Journal of Cosmetic Dermatology, 14(3), 224–232.
January 31, 2025
Azelaic acid is a scientifically proven, multi-functional skincare ingredient naturally present in the skin and produced by Malassezia furfur, a yeast species found in the microbiome. Found in advanced skincare products like Luminous Balance Cream by Luksha Cosmetics it delivers targeted benefits for rosacea, pigmentation, and acne.
This naturally occurring component helps regulate keratinization, reduce inflammation, and inhibit the growth of acne-causing bacteria, making it an essential component of skin health. But how does it work? Let’s explore its dermatological benefits in detail.
Azelaic acid works through multiple mechanisms, making it a standout ingredient for various skin concerns:
Anti-Inflammatory Properties – It helps calm redness and irritation, making it particularly beneficial for rosacea and sensitive skin types.
Antimicrobial Action – It inhibits the growth of acne-causing bacteria, such as Propionibacterium acnes and Staphylococcus epidermidis, helping to prevent breakouts.
Tyrosinase Inhibition – It blocks the enzyme responsible for melanin production, making it an effective treatment for hyperpigmentation and post-inflammatory marks.
Keratin Regulation – It prevents clogged pores by normalizing keratin production, reducing the risk of blackheads and acne.
Hyperpigmentation, including melasma, post-inflammatory hyperpigmentation (PIH), and sunspots, results from overactive melanocytes, the pigment-producing cells in the skin. Azelaic acid inhibits tyrosinase, the enzyme responsible for melanin synthesis, helping to fade dark spots and even out skin tone.
Studies suggest that 10% azelaic acid effectively reduces hyperpigmentation over time, making it a great choice for sensitive skin that may not tolerate stronger treatments. Unlike hydroquinone, azelaic acid is gentler on the skin, making it a safer, long-term option for those with sensitive or reactive skin.
Rosacea is a chronic inflammatory condition that causes persistent redness, visible blood vessels, and sometimes acne-like breakouts. Azelaic acid is one of the most effective, dermatologist-recommended treatments for rosacea due to its anti-inflammatory and antimicrobial properties.
Reduces Redness – Azelaic acid helps reduce inflammation in the skin, decreasing persistent redness and irritation.
Controls Bacterial Overgrowth – It keeps the skin microbiome balanced, preventing the flare-ups common in rosacea-prone individuals.
Strengthens the Skin Barrier – By reducing oxidative stress, it helps reinforce the skin’s protective barrier, minimizing sensitivity.
Clinical evidence suggests that 10% azelaic acid can effectively reduce redness and improve overall skin texture in rosacea-prone individuals.
Acne is a multi-faceted skin concern influenced by excess oil production, bacterial overgrowth, inflammation, and clogged pores. Azelaic acid effectively targets all four factors, making it a powerful yet gentle alternative to harsher acne treatments like benzoyl peroxide or retinoids.
Fights Acne-Causing Bacteria – Azelaic acid inhibits Cutibacterium acnes (C. acnes), reducing the bacterial load responsible for breakouts.
Unclogs Pores – It normalizes keratinization, preventing dead skin cells from accumulating and causing blockages.
Calms Inflammation – Its soothing properties reduce the redness and swelling associated with active acne lesions.
A 10% azelaic acid formula has been shown to reduce acne lesions, unclog pores, and calm inflammation, making it an excellent alternative for sensitive skin.
Azelaic acid is well-tolerated by most skin types, but for best results:
Apply a pea-sized amount once or twice daily after cleansing and before moisturizing (if you have a dry or dehydrated skin, you may need an extra cream or lotion).
Always wear sunscreen, as reducing melanin production can make your skin more prone to UV damage.
It can be safely combined with niacinamide, hyaluronic acid, and sunscreen for enhanced results.
Azelaic acid at 10% concentration is a skincare powerhouse, effectively treating hyperpigmentation, rosacea, and acne with minimal irritation. Its anti-inflammatory, antimicrobial, and melanin-regulating properties make it a go-to ingredient for dermatologists and skincare experts alike. Another excellent example of a well-formulated product featuring 10% Azelaic Acid is Luminous Balance Cream by Luksha Cosmetics, designed to provide maximum efficacy while soothing and brightening the skin.
If you haven’t tried it yet, now might be the perfect time to unlock the full potential of this scientifically proven skincare hero!
Draelos, Z. D. (2006). The Effect of Azelaic Acid on Hyperpigmentation and Acne: A Review of Clinical Evidence.Journal of Clinical and Aesthetic Dermatology.
Gupta, A. K., Gover, M. D. (2011). Azelaic Acid in Dermatology: An Overview of Its Therapeutic Potential.Dermatologic Therapy.
Kircik, L. H. (2019). Azelaic Acid: A Unique Therapy for Rosacea and Acne. Journal of Drugs in Dermatology.
Fitzpatrick, R. E., Gold, L. S. (2010). The Role of Azelaic Acid in Inhibiting Tyrosinase Activity and Melanin Synthesis. International Journal of Cosmetic Science.
Del Rosso, J. Q. (2016). Azelaic Acid: Efficacy and Safety in Treating Rosacea and Acne. Cutis.
January 26, 2025
In Earth’s harshest environments, scientists discovered Antarctic Sea Glycoprotein, also known as Pseudoalteromonas Ferment Extract (Antarcticin), derived from microorganisms thriving in Antarctica’s icy waters. This exceptional ingredient rejuvenates and enhances skin health.
Antarctic Sea Glycoprotein, or Antarcticin, is a compound from bacteria discovered by a Spanish expedition studying Antarctic glaciers. These microorganisms, capable of surviving –50°C, produce glycoproteins that stabilize their structures, prevent ice formation, and retain hydration—properties that also deeply hydrate and strengthen the skin’s barrier. A prime example is the Revitalizing Cream with Antarctic Sea Glycoprotein (Antarcticin) by Luksha Cosmetics, which harnesses these benefits for exceptional skin health. Its bioactive properties lock in moisture and fortify the skin’s barrier, ensuring deep hydration and long-lasting resilience.
The moisture-retaining properties of Antarctic Sea Glycoprotein are perhaps its most celebrated feature. By forming a protective film on the skin’s surface, it reduces transepidermal water loss (TEWL) and locks in hydration. This makes it particularly effective for individuals with dry or dehydrated skin, as well as those exposed to harsh environmental conditions such as cold, wind, or pollution.
Antarctic Sea Glycoprotein acts as a shield for the skin, protecting it from oxidative stress, damage caused by external aggressors, and providing cryoprotection against cold and wind. Its film-forming ability not only prevents water loss but also guards against pollutants and UV-induced damage, enhancing the skin’s natural defense mechanisms.
Studies show Antarctic Sea Glycoprotein increases collagen by up to 114% and elastin by 17% within 15 days, boosting firmness and reducing wrinkles. Collagen is a critical protein that maintains skin firmness, elasticity, and structure. By encouraging collagen production, this ingredient helps reduce the appearance of fine lines and wrinkles while improving skin texture.
Thanks to its bioactive properties, Antarctic Sea Glycoprotein has a soothing effect on the skin, reducing irritation and redness. This makes it an excellent ingredient for sensitive or reactive skin types. Its ability to promote a balanced and calm complexion adds to its appeal for those with rosacea or environmentally stressed skin.
The glycoprotein’s ability to stabilize cellular structures aids in skin regeneration. By stabilizing cellular structures and promoting keratinocyte migration, Antarctic Sea Glycoprotein accelerates the skin’s natural repair processes, making it highly effective in wound healing. It also aids in faster regeneration and overall skin renewal, significantly reducing the appearance of wrinkles. This is particularly beneficial for damaged or aging skin.
This ingredient is suitable for a wide range of skin types and concerns. Whether you have dry, mature, sensitive, or environmentally stressed skin, Antarctic Sea Glycoprotein offers targeted benefits that enhance hydration, repair, and protection. It is especially effective for those living in extreme climates or dealing with the effects of aging.
Antarctic Sea Glycoprotein is often found in serums, moisturizers, and masks designed to deliver hydration and repair. For best results:
Use products containing this ingredient as part of your daily skincare routine.
Pair it with complementary products containing ingredients like hyaluronic acid for enhanced hydration or peptides for anti-aging benefits.
Apply consistently to build long-term resilience and maintain a healthy, luminous complexion.
Antarctic Sea Glycoprotein demonstrates how nature’s toughest environments can inspire groundbreaking skincare, offering deep hydration, improved elasticity, and visible wrinkle reduction. A standout example is the Revitalizing Cream with Antarctic Sea Glycoprotein (Antarcticin) by Luksha Cosmetics, showcasing how this ingredient transforms skin health.
J. P. Bowman et al. (1998) - "Novel Psychrophilic Bacteria from Antarctic Marine Environments: Molecular Ecology and Potential Biotechnological Applications."
F. Cavicchioli et al. (2002) - "Extremophiles and the Limits of Life in a Planetary Context."
M. Mancini et al. (2014) - "Applications of Marine Polysaccharides and Glycoproteins in Skincare Products."
P. P. D’Amico et al. (2006) - "Cold-Adapted Enzymes: From Fundamentals to Biotechnology."
December 05, 2024
When it comes to achieving brighter, smoother, and more resilient skin, 15% L-Ascorbic Acid combined with Ferulic Acid is a gold standard. This powerful pair not only visibly reduces pigmentation and improves texture but also protects your skin from daily environmental damage, making it essential for anyone aiming to maintain youthful, radiant skin.
The Intensive Brightening Serum, with 15% L-Ascorbic Acid, 2% Panthenol, and 0.6% Ferulic Acid, works like magic to create an enviable, radiant glow.
Enhanced with Tetrahydropiperine, a natural extract from black pepper fruit, it boosts the absorption of Vitamin C by 30%, ensuring maximum effectiveness. As a bonus, it also acts as a potent antioxidant, further supporting skin health.
At a clinically effective concentration of 15%, L-Ascorbic Acid (Vitamin C) delivers proven, transformative results:
Ferulic Acid, a potent antioxidant derived from plant sources, works synergistically with L-Ascorbic Acid to enhance efficacy and stability:
When combined, 15% L-Ascorbic Acid and Ferulic Acid offer a scientifically validated, multi-targeted approach to skincare:
Apply Intensive Brightening Serum ones a day in the morning or evening on clean, dry skin, and, if its morning, follow with a broad-spectrum sunscreen or one of your moisturizers such as Eco-Balance Probiotic Radiance Cream with Pomegranate Seed Oil and Coenzyme Q10 or Moisturizing Cream-Mask.
Once absorbed, Intensive Brightening Serum continues to work effectively for at least 72 hours.
Incorporating 15% L-Ascorbic Acid and Ferulic Acid into your routine delivers:
✨ Visibly brighter, more even skin tone
✨ Reduction in pigmentation and discoloration
✨ Firmer, smoother, and more youthful texture
✨ Long-term protection against signs of aging
The science is clear: this dynamic duo is your ticket to healthier, glowing skin. Pair it with sunscreen for a complete, scientifically backed defense against premature aging and environmental stress. Your skin deserves this level of care!
References:
November 12, 2024
Cleansing is essential to keeping our skin healthy, radiant, and free from impurities. However, many of the surfactants found in everyday cleansing products—like soaps, shower gels, and handwashes—can actually disrupt the skin’s natural defense. Although surfactants are effective at removing dirt, they often strip away the protective lipids that maintain our skin’s moisture and resilience. Here’s why the skin barrier matters and how a gentler, oil-based approach can help.
The Skin Barrier: A Layered Defense
Our skin’s outer layer, the stratum corneum, is a carefully structured barrier that protects against environmental damage and moisture loss. It’s composed of corneocytes (flattened skin cells) that act like bricks, and a mixture of lipids that function as the “mortar” holding everything together. These lipids—such as ceramides, fatty acids, and cholesterol—play a critical role in sealing in moisture and keeping irritants out.
The formation of the skin barrier starts with keratinocytes, specialized cells born in the deepest layer of the epidermis. These cells receive nutrients, proteins, and oxygen from blood vessels at this basal layer and then migrate upward through the layers of the epidermis, gradually transforming as they go.
1. Stratum Spinosum: Here, keratinocytes start producing skin lipids, which include ceramides, triglycerides, cholesterol, and fatty acids—each essential for the skin’s protective function.
2. Stratum Granulosum: This is where the keratinocytes transform further, producing keratohyalin granules, which are key to forming filaggrin. Filaggrin is a protein that’s critical for keratinization—the process that strengthens these cells into corneocytes. At this stage, the cells also complete their lipid production, finalizing the mortar that will hold the skin’s “brick wall” together.
3. Stratum Corneum: By the time keratinocytes reach this top layer, they have become tough, flattened corneocytes. They release the skin lipids to form a structured layer around them, creating a flexible yet strong barrier against the environment. The stratum corneum is only a few micrometers thick, yet it is essential for protecting the body and preserving hydration.
Natural Moisturizing Factor (NMF)
The skin barrier also contains natural moisturizing factor (NMF), which forms as filaggrin breaks down into amino acids. This NMF is water-soluble and attracts and holds water, helping keep the stratum corneum flexible and hydrated. The combination of NMF and skin lipids creates a lamellar (layered) structure that acts as a flexible seal, keeping moisture in and external stressors out.
Sebum: The Skin’s “Day Cream”
Adding to the skin barrier, sebum produced by the sebaceous glands forms an additional protective layer over the stratum corneum. Sebum contains triglycerides, fatty acids, wax esters, and vitamin E. This “natural day cream” offers several benefits, such as neutralizing free radicals with vitamin E, blocking harmful microbes, and nourishing the skin microbiota. Together, the stratum corneum, NMF, and sebum act as a trio that maintains the skin’s hydration and resilience.
The Problem with Most Surfactant-Based Cleansers (Foaming washes, gels, soaps, etc.)
Surfactants, with their unique ability to bind both water and oil, make for highly effective cleansers. However, they can’t distinguish between dirt and essential skin lipids. As they lift away impurities, they often remove these valuable lipids too, weakening the barrier. Over time, repeated exposure to surfactants, even milder ones like Lauryl Glucoside, leads to increased transepidermal water loss (TEWL), making skin dry and sensitive.
Studies on commonly used surfactants like Sodium Laureth Sulfate (SLES) and Sodium Lauryl Sulfate (SLS) show concerning results: SLES increases TEWL by 866%, and even the mild Lauryl Glucoside (LG) increases the TEWL by 241%. This is significant, as it takes three weeks for keratinocytes to produce and arrange these lipids, yet surfactants can strip them away in seconds.
A Gentler Solution: Rice Bran Oil-Based Cleansing
To help preserve the skin’s natural balance, a gentler alternative like rice bran oil offers a promising approach. Unlike surfactants, which can strip away essential lipids, rice bran oil dissolves impurities while respecting the skin’s protective barrier. This means it effectively removes dirt and makeup without disrupting the skin’s natural moisture, helping it stay hydrated and resilient against environmental stressors.
Rice bran oil is an exceptional moisturizer and a rich source of skin-loving nutrients, including vitamin E, Coenzyme Q10, squalane, and omega-6 fatty acids. These ingredients work together to support wound healing, promote skin regeneration, and enhance the skin’s overall health and elasticity.
Luksha Cosmetics Cleansing Oil, based on rice bran oil mixed with gentle skin-friendly emulsifier, harnesses the power of rice bran oil to cleanse effectively without compromising the skin’s natural lipids. This cleansing product gently dissolves dirt, makeup, and sebum without stripping away the essential fatty acids that keep your skin hydrated and resilient.
By choosing Luksha’s rice bran oil-based cleansing solution, you can maintain the health and integrity of your skin barrier while enjoying the benefits of a thorough yet gentle cleanse. This approach honors your skin’s natural processes, offering protection, hydration, and a lasting glow.
References:
1. (Rawlings, A. V., & Matts, P. J. (2005). “Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle.” Journal of Investigative Dermatology, 124(6), 1099-1110.
2. Pugh, W. J., & Griffiths, S. (2001). “Surfactants and skin barrier function.” Journal of Cosmetic Science, 52(2), 161-168.
3. Le Poole, H. A. C., & Van Den Wijngaard, R. M. J. G. (2014). “The challenge of cleansing and treating sensitive skin.” Skin Pharmacology and Physiology, 27(3), 121-132.
4. Draelos, Z. D. (2018). “The science behind skin cleansing.” International Journal of Cosmetic Science, 40(4), 341-347.
5. Lodén, M., & Maibach, H. I. (2000). “Treatment of dry skin syndrome: The art and science of moisturizers.” CRC Press.
6. Lodén, M. (2003). “The clinical benefit of moisturizers.” Journal of the European Academy of Dermatology and Venereology, 17, 2-8.
7. Draelos, Z. D. (2013). “The essentials of clinical research in cosmetic science.” Dermatologic Clinics, 31(4), 625-632.
October 18, 2024
Matrixyl™ 3000 and Argireline® Amplified are two powerhouse peptides in the world of anti-aging skincare, delivering remarkable results for mature skin. Found in our Contouring Multi-Action Cream and Uplifting Eye Cream, these ingredients work together to smooth wrinkles, boost firmness, and refine texture. Backed by cutting-edge science, these peptides dive deep at the molecular level, rejuvenating your skin and restoring a youthful glow. It's no wonder they're key players in any effective anti-aging routine!
Matrixyl™ 3000 is a synergistic blend of palmitoyl tripeptide-1 (C33H65N5O5) and palmitoyl tetrapeptide-7 (C38H68N8O8), both of which are matrikines—messenger peptides capable of regulating cell activities by interacting with their specific receptors. They activate certain genes involved in the process of extracellular matrix renewal and cell proliferation. These mechanisms become weaker and weaker with age.
. These peptides act as signaling molecules that stimulate the skin to repair itself, much like its natural wound-healing process.
Palmitoylation for Enhanced Penetration: The palmitoyl group in Matrixyl™ 3000 (a fatty acid chain) increases the peptide’s lipophilicity, allowing it to penetrate the lipid barrier of the skin more effectively. This deeper penetration ensures the peptides reach the fibroblasts in the dermis, where collagen production takes place.
Collagen Synthesis via MMP Inhibition: Matrixyl™ 3000 works by inhibiting matrix metalloproteinases (MMPs)—enzymes that break down collagen and elastin in the skin. By reducing MMP activity, Matrixyl™ 3000 helps preserve the skin's structural integrity, encouraging fibroblast activity and promoting the synthesis of types I, III, and IV collagen. The result is increased skin firmness and reduced wrinkle depth.
Anti-Inflammatory Properties: Palmitoyl tetrapeptide-7, one of the key components of Matrixyl™ 3000, also reduces the production of pro-inflammatory cytokines, such as interleukin-6 (IL-6), which are elevated during the aging process. By modulating inflammation, Matrixyl™ 3000 helps prevent collagen degradation and soothes mature, sensitive skin.
In Vivo Tests:
28 female volunteers aged from 51 to 72 years, mean age 59. Twice daily application of a cream containing 3% of Matrixyl®3000 for 2 months to one half of the face and the forearm (inner and UV-exposed outer forearm) against placebo.
Argireline® Amplified (acetyl hexapeptide-8: C34H60N14O12S) is a synthetic hexapeptide derived from SNAP-25 (a substrate of the neurotoxin pathway) that works by interrupting the SNARE complex—a set of proteins required for synaptic vesicle release. This inhibition reduces the release of acetylcholine, a neurotransmitter that triggers muscle contractions. As a result, the muscles beneath the skin relax, leading to a reduction in dynamic wrinkles, such as crow’s feet and forehead lines.
SNARE Complex Modulation: The SNARE (Soluble NSF Attachment Protein Receptor) complex plays a crucial role in muscle contraction by facilitating the release of acetylcholine from neurons. By modulating this process, Argireline® Amplified weakens the signal for muscle movement. Unlike invasive treatments like Botox, which completely block muscle contraction, Argireline® Amplified subtly relaxes facial muscles, making it a safer, non-invasive alternative for daily use.
Effectiveness on Dynamic Wrinkles: Dynamic wrinkles, caused by repetitive muscle contractions over time, can deepen as skin loses elasticity with age. Argireline® Amplified specifically targets these expression lines by reducing muscle tension, effectively preventing further deepening of wrinkles.
Peptide Structure and Skin Penetration: Argireline® Amplified is a small peptide that mimics the N-terminal end of SNAP-25, blocking the vesicle fusion necessary for neurotransmitter release. Its size and structure make it effective in penetrating the upper layers of the skin and reaching the targeted neuromuscular junctions to inhibit micro-contractions.
In Vivo Tests: Two panels of 40 and 41 female volunteers between 34-60 years old. Half face application. Expression wrinkles: Evaluated using PRIMOS 3D.
The combination of Matrixyl™ 3000 and Argireline® Amplified provides a multifaceted approach to aging skin by addressing both structural integrity and dynamic wrinkle formation.
Collagen Stimulation + Muscle Relaxation: While Matrixyl™ 3000 works to repair the skin’s extracellular matrix by boosting collagen and elastin production, Argireline® Amplified prevents mechanical stress from muscle contractions that exacerbate wrinkle formation. This dual action helps improve skin firmness while smoothing out expression lines for a more youthful appearance.
Firming and Smoothing: Matrixyl™ 3000 helps restore the skin’s firmness by promoting collagen and hyaluronic acid production, while Argireline® Amplified prevents the mechanical stress caused by muscle movement. Together, they enhance skin elasticity and smoothness.
Hydration and Barrier Support: Matrixyl™ 3000 contributes to improved moisture retention by enhancing hyaluronic acid synthesis, which is essential for mature skin prone to dryness. Argireline® Amplified supports barrier function by reducing mechanical stress on the skin, helping it maintain its resilience.
Matrixyl™ 3000 and Argireline® Amplified are powerful tools in the fight against aging, working together to target wrinkles, loss of firmness, and skin texture. By boosting collagen and relaxing dynamic wrinkles, these peptides offer a comprehensive solution for more youthful, resilient skin.
For those looking to incorporate these potent ingredients into their routine, our Contouring Multi-Action Cream contains both Matrixyl™ 3000 and Argireline® Amplified, providing a double-action effect that lifts and smooths the skin. Additionally, our Uplifting Eye Cream combines Argireline® Amplified with Pentapeptide-18, a peptide known for its synergistic wrinkle-reducing effect when used with Argireline® Amplified. With the highest working concentration of these actives, these products are formulated to deliver visible results, leaving your skin looking firm, smooth, and radiant.
Achieve your best skin with these scientifically-backed ingredients and experience the transformation firsthand.
References:
1. Lintner, K., & Peschard, O. (2000). Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. International Journal of Cosmetic Science, 22(3), 207–218.
2. Schagen, S. K. (2017). Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetic Dermatology, 16(3), 142-149.
3. Blanes-Mira, C., Clemente, J., Jodas, G., et al. (2002). A synthetic hexapeptide (Argireline) with antiwrinkle activity. International Journal of Cosmetic Science, 24(5), 303–310.
4. Bos, J. D., & Meinardi, M. M. (2000). The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Experimental Dermatology, 9(3), 165–169.
5. Fields, K., Falla, T. J., Rodan, K., & Bush, L. (2009). Topical argireline in the treatment of lines and wrinkles: A randomized controlled trial. Journal of Clinical Aesthetic Dermatology, 2(5), 28-34
September 09, 2024
Oxygen is essential for life, but it also has a complex and sometimes harmful relationship with our skin. At Luksha Cosmetics, we embrace this dual role by developing products that enhance skin health while protecting against oxidative stress. Our commitment to the latest research allows us to harness oxygen’s benefits while mitigating its risks.
Oxygen: Essential Yet Complex
Oxygen (O₂), commonly referred to as dioxygen, is a molecule composed of two oxygen atoms and is essential for the survival of all aerobic organisms. While it is widely known for its critical role in generating cellular energy in the form of ATP through the mitochondrial respiratory chain, oxygen is also crucial for numerous physiological functions and biochemical processes. It participates in cell signaling, regulates vascular tone and gene expression, and contributes to the body's antimicrobial defense mechanisms.
Despite the fact that ambient air contains approximately 21% oxygen (160 mm Hg), oxygen concentrations within different organs are significantly lower. These levels are finely tuned to match each organ’s vascularization, function, metabolism, and energy demands. This is especially true for the skin, which displays distinct oxygen concentration gradients.
Skin Physioxia: The Importance of Oxygen Gradients
Oxygen, while essential for life, has a dual role in tissue health. Though vital, it can also be harmful by contributing to the production and accumulation of reactive oxygen species (ROS), which damage cell components like proteins, lipids, and DNA. These ROS, formed as by-products of oxygen metabolism, include both radical and non-radical species and are produced within various cell compartments or triggered by external factors such as UV exposure, pollution, smoking, stress, lack of sleep, and lifestyle choices.
Oxidative stress occurs when there is an imbalance—too many ROS and an overwhelmed antioxidant system unable to neutralize them. This imbalance is a key driver of aging, a theory first proposed by Denham Harman in 1956, known as the "Free Radical Theory of Aging." Additionally, ROS influence cell signaling pathways like MAPK and NF-kB, which, when overactivated, trigger the production of matrix metalloproteinases (MMPs) responsible for breaking down the extracellular matrix (ECM), leading to "inflammaging." This process is particularly evident in photoaging, where overexpression of MMP-1, MMP-3, and MMP-9 accelerates skin aging.
While UV exposure is a well-known cause of extrinsic skin aging, other factors like visible light, infrared radiation, and pollutants also play a significant role in premature aging. As a result, industry experts are working to develop solutions that protect the skin from these environmental stressors.
Luksha Cosmetics’ Innovative Approaches
At Luksha Cosmetics, we have adopted several advanced strategies to counteract the harmful effects of oxygen while promoting its skin health benefits.
1. Contouring Multi-Action Cream
Our Contouring Multi-Action Cream is a standout example of how we combine cutting-edge science with effective skincare solutions. This cream is packed with powerful antioxidants to combat oxidative stress, featuring:
- Coenzyme Q10: A powerful antioxidant that protects the skin from environmental damage while reducing the appearance of fine lines and wrinkles. It also supports natural collagen production, improving skin firmness and elasticity.
- Tetrahexyldecyl Ascorbate: A stable, oil-soluble form of Vitamin C known for its outstanding antioxidant and skin-brightening properties.
- Vitamin E: Another potent antioxidant that protects the skin from free radical damage, aids in skin repair, and supports the skin barrier, making the skin appear healthier and more youthful.
The combination of these ingredients makes the Contouring Multi-Action Cream a powerful tool in defending against the harmful effects of oxidative stress while promoting a more youthful and firm complexion.
Our Nourishing Cream blends antioxidants like Raspberry Seed Oil and Vitamin E to fight oxidative damage and improve skin repair. This cream helps improve skin tone and shield the skin from environmental stressors, ensuring a radiant and youthful look.
3. Eco-Balance Probiotic Night Cream
This cream reduces oxidative stress by strengthening and supporting the skin’s microbiome, helping to promote a healthier, more balanced complexion.
This product boasts a powerful form of Vitamin E that not only combats oxidative stress but also delivers intense hydration, leaving your skin nourished, protected, and radiant.
The Future of Skincare and Oxygen
At Luksha Cosmetics, we understand the dual role of oxygen in skin health, and our goal is to develop products that both leverage its benefits and protect against its potential harm. By incorporating antioxidants and respecting the skin’s natural oxygen gradient, we create solutions that not only improve skin health but also prevent premature aging.
As research evolves, at Luksha Cosmetics will continue to offer advanced, targeted skincare solutions that respect the balance of oxygen in the skin, ensuring our clients experience the best in both protection and skin vitality.
References:
July 20, 2024
Have you ever wondered why your skin looks the way it does? Skin pigmentation and color vary widely, influenced by genetics, geographical location, and sun exposure. While the idea of the perfect skin tone has evolved over time, many people still seek that radiant, even complexion. From ancient beauty rituals to modern skincare routines, the quest for luminous skin has always been a fascinating journey.
So, what gives our skin its color? The magic lies in melanin, the pigment produced by melanocytes. There are two types of melanin: eumelanin (which gives black and brown hues) and pheomelanin (which adds red and yellow tones). The balance of these pigments determines our unique skin and hair colors. The key player in this process is the enzyme tyrosinase, which converts L-tyrosine to L-DOPAquinone, leading to the production of melanin. Tyrosinase is the key enzyme that determines the pigmentation of the skin and the intensity of pigment spots.
The cosmetic industry has long been on the hunt for the perfect skin-lightening ingredients. The goal? To find compounds that not only lighten skin effectively but also do so without causing irritation. This has led to the exploration of many ingredients, some of which have proven effective but come with restrictions due to their potential side effects. The exciting news is that new, skin-friendly options are emerging, thanks to advances in science and technology.
One of the standout ingredients in the world of skin lightening is N-Acetylglucosamine (NAG). This little powerhouse is a monosaccharide derived from glucose and chitin, which is naturally found in the shells of crustaceans. What makes NAG so special? It inhibits the conversion of protyrosinase to tyrosinase, effectively reducing pigmentation.
In an impressive 8-week split-face study, a combination of 2% NAG and 4% niacinamide (another skincare superstar) reduced pigmentation by 30%. Niacinamide helps by preventing melanosomes (pigment packets) from transferring to skin cells, enhancing the lightening effect.
Here at Luksha, we believe in combining the best of science and nature to create products that make you feel amazing. Our Intensive Hydrating Serum is a perfect example. It features not only the powerful humectant Hyaluronic Acid—both Medium and Super Low Molecular—but also skin-lightening, skin-friendly components like NAG and niacinamide. This serum works wonders by hydrating deeply and helping to even out skin tone, giving you that coveted glow.
The journey to finding effective and gentle skin-lightening ingredients is an ongoing adventure. With the help of innovative ingredients like NAG and the benefits of niacinamide, we can create products that enhance your skin's natural beauty. At Luksha, we're committed to developing skincare solutions that not only meet your needs but also inspire confidence and joy.
So, whether you're looking to brighten your complexion or simply want to learn more about the magic behind your skincare, remember that every product has a story. And at Luksha, that story is all about celebrating the beauty and uniqueness of your skin.
By understanding how these ingredients work and incorporating them into your routine, you can achieve a healthier, more radiant complexion. Dive into the world of skincare with us, and discover the difference that thoughtful, scientifically-backed products can make.
References:
1. Del Bino S, Duval C, Bernerd F. Clinical and Biological Characterization of Skin Pigmentation Diversity and Its Consequences on UV Impact. Int J Mol Sci 2018, 19.
2. Jablonski NG, Chaplin G. Colloquium paper: human skin pigmentation as an adaptation to UV radiation. Proc Natl Acad Sci US A 2010, 107 Suppl 2: 8962-8968.
3. Mann T, Gerwat W, Batzer J, Eggers K, Scherner C, Wenck H, et al. Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase. Journal of Investigative Dermatology 2018, 138: 1601-1608.
4. Jin YH, Lee SJ, Chung MH, Park JH, Park YI, Cho TH, et al. Aloesin and arbutin inhibit tyrosinase activity in a synergistic manner via a different action mechanism. Archives of pharmacal research 1999, 22: 232-236.
5. Nokinsee D, Shank L, Lee VS, Nimmanpipug P. Estimation of Inhibitory Effect against Tyrosinase Activity through Homology Modeling and Molecular Docking. Enzyme Res 2015, 2015: 262364.
6. Wang Z, Xiang H, Dong P, Zhang T, Lu C, Jin T, et a/. Pegylated azelaic acid: Synthe-sis, tyrosinase inhibitory activity, antibacterial activity and cytotoxic studies. Journal of Molecular Structure 2021, 1224: 129234.
7. Jirawattanapong W, Saifah E, Patarapanich C. Synthesis of glabridin derivatives as tyrosinase inhibitors. Arch Pharm Res 2009, 32: 647-654.