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News

Smart Skincare Starts Here: The Science Behind Cellular Cream

May 01, 2025

Smart Skincare Starts Here: The Science Behind Cellular Cream

What if your skincare routine could do more than hydrate and soften—what if it could activate your skin’s own biological intelligence? Luksha’s Cellular Cream is built on this philosophy. It combines advanced biomimetic actives and clinically studied botanical technologies to target aging at its source—from deep dermal restructuring to epidermal renewal.

This multi-layered approach leverages three exceptional ingredients: Gladback™, a dermal fortifier derived from medicinal mycology; Decorinyl®, a peptide that mimics skin’s structural regulators; and PhytoCellTec™ Malus Domestica, a patented apple stem cell technology that helps preserve skin’s regenerative power. Each ingredient plays a precise role, working in synergy to help your skin look and function at its best.

1. PhytoCellTec™ Malus Domestica (Apple Stem Cell Extract, Switzerland

Inspired by the longevity of the rare Swiss apple Uttwiler Spätlauber, this stem cell technology supports the skin’s own epidermal stem cells—the source of continuous skin renewal.


Mechanism of Action:

  • Shields human epidermal stem cells from UV-induced oxidative stress and apoptosis, preserving their function over time 

  • Enhances mitochondrial activity and ATP synthesis, energizing basal keratinocytes for improved epidermal turnover.

  • Clinically proven to reduce wrinkle depth by 15% within 4 weeks, contributing to smoother, more youthful-looking skin.

  • Liposomal encapsulation ensures penetration to the basal layers where stem cells reside.

2. Gladback™ (Poria cocos-based active for mature skin), Spain

Gladback™ is derived from Poria cocos, a revered medicinal mushroom used in Traditional Chinese Medicine. It offers targeted support for mature, stressed, or hormonally imbalanced skin.


Mechanism of Action:

  • Increases dermal thickness and microvascular density, improving skin firmness and tone. Clinical ultrasound imaging confirmed enhanced dermal echogenicity in postmenopausal subjects after 28 days of use.

  • Stimulates collagen I synthesis while suppressing MMP-1 activity, protecting the extracellular matrix from breakdown.

  • Brightens and revitalizes the skin by improving oxygen and nutrient delivery through enhanced microcirculation.

  • Delivers antioxidant and anti-inflammatory benefits via triterpene compounds, mitigating oxidative stress and inflammaging.

3. Decorinyl® – Tripeptide-10 Citrulline Complex, France

Decorinyl® is a biomimetic peptide inspired by decorin, a natural regulator of collagen fiber organization. As skin ages, collagen becomes irregular and fragmented—this peptide helps restore structure.

54% increase in skin suppleness after 28 days.


Mechanism of Action:

  • Modulates collagen fibril spacing and diameter, improving mechanical properties and elasticity.

  • Reduces wrinkle depth and surface roughness. In clinical trials, participants saw up to a 14% improvement in skin smoothness after 4 weeks of use.

  • Controls MMP activity to maintain balanced matrix turnover and prevent degradation of structural proteins.

  • Uses a phospholipid-based delivery system (lecithin) to optimize bioavailability, while caprylyl glycol maintains hydration and product stability.

Conclusion:

Cellular Cream is a meticulously engineered formulation developed to support the skin’s structural integrity and long-term vitality. Its fresh, small-batch production ensures maximum potency and stability, avoiding the compromises of mass manufacturing.

Designed with both precision and purpose, this cream works in harmony with the skin’s own biology—delivering visible results while respecting its natural rhythm.

 

References:

  1. Li, J. et al. (2019). Anti-inflammatory effects of Poria cocos polysaccharides in macrophages. Journal of Ethnopharmacology, 241, 112549.

  2. Lee, B. et al. (2018). Poria cocos-derived polysaccharides regulate tight junction proteins. Archives of Pharmacal Research, 41, 1236–1244.

  3. Kim, S. et al. (2021). Hydrating effects of β-glucans and AQP3 stimulation. Cosmetics, 8(3), 76.

  4. Zampar, A. et al. (2010). Role of decorin in collagen organization. Biochimica et Biophysica Acta, 1802(10), 1004–1010.



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