The menopause was once a taboo topic — but today, it’s openly discussed, and rightly so. With longer lifespans and greater awareness of women’s health, the beauty industry is now being challenged to deliver meaningful, science-driven solutions for mature and menopausal skin.
At Luksha Cosmetics®, we’ve been studying how hormonal transitions affect the skin at a cellular level. We have been able to confirm an impressive ability to enhance overall skin health and resilience of post-menopausal skin, with significant results in addressing many changes that affect not only the skin’s appearance but also women’s confidence during this multi-change period.
During menopause, declining and fluctuating levels of estrogen and progesterone disrupt the hormonal balance that keeps the skin firm, hydrated, and luminous. Estrogen receptors are found throughout the skin — particularly in fibroblasts, keratinocytes, and endothelial cells — where they regulate the production of collagen types I and III, elastin, hyaluronic acid, and key lipids responsible for barrier integrity.
As estrogen levels fall, fibroblast activity decreases by up to 40%, reducing collagen synthesis and weakening dermal density. Within the first five years post-menopause, women can lose as much as 30% of skin collagen, and about 2% each year thereafter. The epidermal turnover also slows, leading to a rougher texture and delayed healing.
Meanwhile, the extracellular matrix (ECM) — the skin’s structural scaffolding — becomes disorganized as glycosaminoglycan and proteoglycan content declines. Reduced estrogen and progesterone signaling also compromise the skin’s microvascular network, impairing nutrient and oxygen delivery. The combined effect is slower metabolism, dullness, dryness, and a visible loss of elasticity and radiance.
In essence, menopausal skin doesn’t just age chronologically — it undergoes a profound metabolic shift, requiring targeted support to restore communication between cells, reinforce the ECM, and revive microcirculation.
Our Cellular Cream was created specifically to support the complex needs of mature, post-menopausal skin.
Beyond its Swiss plant stem cell technology, this advanced formula features Poria Cocos Polysaccharide — a bioactive derived from a medicinal mushroom long used in traditional Asian medicine. Modern research has shown its ability to improve skin thickness, boost microcirculation, and enhance radiance by stimulating fibroblast activity and improving oxygen and nutrient exchange in the dermis.
Another key component is Tetrapeptide-10 Citrulline, a biomimetic peptide that helps rebuild the skin’s supportive matrix by increasing collagen and elastin organization. In clinical evaluations, it has been shown to improve skin firmness by up to 28% and elasticity by 19% in just two weeks, while visibly refining surface texture.
Together, these ingredients form a powerful, restorative complex designed to help the skin regain the qualities it naturally loses during hormonal transition — density, hydration, resilience, and glow.
Menopausal skincare isn’t about turning back time. It’s about helping skin — and women — adapt to change with strength and grace. Our goal at Luksha is to work with the skin’s biology, supporting its natural repair and renewal processes rather than masking symptoms.
With consistent use, Cellular Cream helps restore a sense of balance and radiance, leaving the skin visibly smoother, firmer, and more comfortable — a reflection of inner vitality at every stage of life.
Menopause isn’t a malfunction — it’s a recalibration of brilliance!
References:
Thornton MJ. Estrogens and aging skin. Dermatoendocrinol. 2013;5(2):264–270.
Rzepecki AK, et al. Estrogen-deficient skin: the role of topical therapy. Int J Women’s Dermatol. 2019;5(2):85–90.
Bravo B, et al. Dermatological changes during menopause and HRT. Cosmetics. 2024;11(1):9.
Viscomi B, et al. Managing menopausal skin changes: a narrative review. J Clin Med. 2025.
Trehan S, et al. Plant stem cells in cosmetics: current trends and future perspectives. J Cosmet Dermatol. 2017.
Aggarwal S, et al. Plant stem cells and their applications. Appl Biochem Biotechnol. 2020.
Raikou V, et al. The efficacy of tripeptide-10 citrulline and acetyl hexapeptide-3: a randomized controlled study. J Cosmet Dermatol. 2017;16(2):271–278.
Badilli U, et al. Current approaches in cosmeceuticals: peptides, biotics and novel actives. Cosmetics. 2025.
Schagen SK. Topical peptide treatments with effective anti-aging results. Cosmetics. 2017;4(2):16.
